Early Menopause and Blood Sugar: What Every Woman Needs to Know by Age 35

Most high-achieving women are so busy caring for their families, careers, and communities that their own preventive health screenings often fall to the bottom of the list. But here’s one that cannot wait: everyone—women included—should be screened for type 2 diabetes by age 35 at the latest, according to the American Diabetes Association’s latest guidelines.

And for women approaching or experiencing menopause, especially before age 45, it’s even more critical.

The Menopause–Diabetes Connection

Menopause is more than hot flashes and mood swings. The hormonal shifts associated with menopause symptoms—particularly declining estrogen—have a profound impact on metabolism. As estrogen levels drop, women tend to experience increased belly fat, decreased energy expenditure, and higher insulin resistance, all of which can cause rising blood sugar levels over time.

These changes push many women into the prediabetic range without symptoms—and without knowing it.

Early Menopause Means Higher Diabetes Risk

Women who go through menopause before age 45 have a 15–32% increased risk of developing type 2 diabetes compared to women whose menopause occurs between 50 and 54 years. The risk is even higher for women with premature ovarian insufficiency (menopause before age 40), and this association holds even if you’re not overweight and don’t smoke.

That’s right—your menopausal status alone is a risk factor, and it’s not something most doctors discuss during routine visits.

Why Estrogen Matters for Blood Sugar

Estrogen isn’t just a reproductive hormone—it’s a metabolic powerhouse. It helps regulate fat distribution, energy use, and how your body responds to insulin. So when estrogen levels decline, your body becomes more insulin resistant, which can push you out of the blood sugar healthy range and into prediabetes or diabetes territory.

Postmenopausal women of all ethnicities face an increased prevalence of type 2 diabetes, with the strongest links seen in White, Japanese, and Chinese women.

What You Can Do Now

  1. Get screened by age 35—or earlier if you've had early menopause, gestational diabetes, PCOS, or a family history of diabetes.

  2. Track your fasting blood sugar levels regularly. A normal fasting glucose is below 100 mg/dL, while 100–125 mg/dL signals prediabetes.

  3. Ask your doctor whether Menopausal Hormone Therapy (MHT) may benefit you. While not recommended solely for diabetes prevention, studies suggest MHT may reduce your risk if used for menopausal symptoms and started near the time of menopause.

Bottom Line

Your hormonal history matters. If you’ve gone through early menopause, you deserve proactive care—not just reactive treatment. Diabetes screening isn’t just for people with weight concerns—it’s for every woman, and it could change the trajectory of your health.


 Want personalized care that connects your hormones to your metabolic health? Schedule a virtual visit with one of our expert endocrinologists who understand the unique needs of high-achieving women.

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FAQs

What’s the best blood sugar healthy range for women in menopause?
A fasting blood sugar under 100 mg/dL and an A1c under 5.7% are considered optimal.

Should I get screened if I feel fine?
Yes—most women with prediabetes have no symptoms. Don’t wait for a wake-up call.

Can hormone therapy prevent diabetes?
MHT may help improve blood sugar in some women, but it’s not approved solely for prevention. Talk to your doctor about risks and benefits.

Arti Thangudu, MD

CEO/Founder HeyHealthy & Complete Medicine

Triple Board Certified in Endocrinology/Diabetes/Metabolism, Internal Medicine, Lifestyle Medicine

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Dr. Arti Thangudu on the "As a Woman" Podcast: What Everybody Needs to Know About Insulin Resistance

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